Hydrochloric Acid → 4-Chloro-5-(3-pyridylmethoxy)-7-[1-(tert-butoxycarbonyl)-5-(piperidin-1-ylmethyl)indol-2-yl]isoindolinone
Reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[CH3:52][C:53]#[N:54].[Cl:1][c:2]1[c:3]2[c:7]([c:8](-[c:12]3[n:13]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[c:14]4[cH:15][cH:16][c:17]([CH2:21][N:22]5[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]5)[cH:18][c:19]4[cH:20]3)[cH:9][c:10]1[OH:11])[C:6](=[O:35])[NH:5][CH2:4]2.[ClH:42].[Cs+:40].[Cs+:41].[OH2:51].[n:43]1[cH:44][c:45]([CH2:49][Cl:50])[cH:46][cH:47][cH:48]1>>[Cl:1][c:2]1[c:3]2[c:7]([c:8](-[c:12]3[n:13]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[c:14]4[cH:15][cH:16][c:17]([CH2:21][N:22]5[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]5)[cH:18][c:19]4[cH:20]3)[cH:9][c:10]1[O:11][CH2:49][c:45]1[cH:44][n:43][cH:48][cH:47][cH:46]1)[C:6](=[O:35])[NH:5][CH2:4]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-30cde77469be41889a8336de89f4b36e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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