1-Butanol → 2-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-(5-(5-(1-(dimethylamino)-2-methylpropan-2-yloxy)pyridin-2-ylamino)-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)-benzyl acetate
Reaction equation
[C:1]([CH3:2])(=[O:3])[O:4][CH2:5][c:6]1[c:7](-[n:21]2[c:22](=[O:36])[c:23]3[c:24]([F:35])[cH:25][c:26]([C:31]([CH3:32])([CH3:33])[CH3:34])[cH:27][c:28]3[cH:29][n:30]2)[cH:8][cH:9][cH:10][c:11]1[B:12]1[O:13][C:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[O:20]1.[CH2:61]([OH:62])[CH2:63][CH2:64][CH3:65].[CH3:67][CH2:68][O:69][C:70](=[O:71])[CH3:72].[Cl:37][c:38]1[cH:39][c:40]([NH:46][c:47]2[n:48][cH:49][c:50]([O:53][C:54]([CH2:55][N:56]([CH3:57])[CH3:58])([CH3:59])[CH3:60])[cH:51][cH:52]2)[c:41](=[O:45])[n:42]([CH3:44])[n:43]1.[OH2:66]>>[C:1]([CH3:2])(=[O:3])[O:4][CH2:5][c:6]1[c:7](-[n:21]2[c:22](=[O:36])[c:23]3[c:24]([F:35])[cH:25][c:26]([C:31]([CH3:32])([CH3:33])[CH3:34])[cH:27][c:28]3[cH:29][n:30]2)[cH:8][cH:9][cH:10][c:11]1-[c:38]1[cH:39][c:40]([NH:46][c:47]2[n:48][cH:49][c:50]([O:53][C:54]([CH2:55][N:56]([CH3:57])[CH3:58])([CH3:59])[CH3:60])[cH:51][cH:52]2)[c:41](=[O:45])[n:42]([CH3:44])[n:43]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ee260d9b63764b7aa20b82cdafea27b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…