Acetic Anhydride → 1-(4-benzyl-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)ethanone

HRID 168996Notes

Reaction equation

HRID 168996 reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[c:15]1[c:16]2[c:17]([n:18][c:19]([NH:21][c:22]3[cH:23][c:24]([O:34][CH3:35])[c:25](-[n:28]4[cH:29][n:30][c:31]([CH3:33])[cH:32]4)[cH:26][cH:27]3)[n:20]1)[CH2:36][CH2:37][NH:38][CH2:39]2.[CH3:1][C:2](=[O:3])[O:4][C:5](=[O:6])[CH3:7]>>[CH3:1][C:2](=[O:3])[N:38]1[CH2:37][CH2:36][c:17]2[c:16]([c:15]([CH2:8][c:9]3[cH:10][cH:11][cH:12][cH:13][cH:14]3)[n:20][c:19]([NH:21][c:22]3[cH:23][c:24]([O:34][CH3:35])[c:25](-[n:28]4[cH:29][n:30][c:31]([CH3:33])[cH:32]4)[cH:26][cH:27]3)[n:18]2)[CH2:39]1

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 8028TetrahydrofuranHCID 593336984-Benzyl-N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Product 1

HCID 593337471-(4-benzyl-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl)ethanone

Sources & evidence

ORD record
ord-400c66f7a26d49a683f17c3751a0af71
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…