HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxy-2-(pyrrolidin-1-yl)-5-aminopyridine → N-[4-Methoxy-6-(pyrrolidin-1-yl)pyridin-3-yl]-5-trifluoromethyl-1-[(4-pyridyl)methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxy-2-(pyrrolidin-1-yl)-5-aminopyridine | HCID 57431519 | — |
| Reactant | 5-Trifluoromethyl-1-[(4-pyridyl)methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid | HCID 66646921 | — |
| Product | N-[4-Methoxy-6-(pyrrolidin-1-yl)pyridin-3-yl]-5-trifluoromethyl-1-[(4-pyridyl)methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | HCID 66907463 | — |
Reaction Steps
The method described in Example 12.3 is followed, starting from 5-amino-4-methoxy-2-(pyrrolidin-1-yl)pyridine, prepared in the preceding stage, and 5-trifluoromethyl-1-[(4-pyridyl)methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid prepared in Stage 9.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153650B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-e1c4f342da7e40eea8014998198db853 |
| Source note | uspto-grants-2012_04 |