HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexyl isocyanate → 1-Benzyl-1-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexyl isocyanate | HCID 18502 | — |
| Reactant | Benzyl-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-amine | HCID 66905008 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-Benzyl-1-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-urea | HCID 45110743 | — |
Reaction Steps
In analogy to the procedure described in example 1.2, benzyl-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-amine was reacted with cyclohexylisocyanate ([3173-53-3]) in toluene for 48 h under reflux conditions to give the title compound as yellow solid. MS: m/e=459.4 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153663B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-1e5ca2a3fc2a4073bc2987c9bb4e32b7 |
| Source note | uspto-grants-2012_04 |