Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1690544Generated: November 1, 2026

[2-(4-Chloro-phenyl)-2H-indazol-3-yl]-phenyl-amine → 3-Chloro-4-{3-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-phenyl-ureido}-benzoic acid methyl ester

https://huagongshe.com/reaction/1690544

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[2-(4-Chloro-phenyl)-2H-indazol-3-yl]-phenyl-amineHCID 66905358—
Reactant3-Chloro-4-isocyanato-benzoic acid methyl esterHCID 86640262—
SolventTolueneHCID 1140—
Product3-Chloro-4-{3-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-phenyl-ureido}-benzoic acid methyl esterHCID 45111024—

Reaction Steps

In analogy to the procedure described in example 1.2, [2-(4-chloro-phenyl)-2H-indazol-3-yl]-phenyl-amine (example 15.1) was reacted with 3-chloro-4-isocyanato-benzoic acid methyl ester (example 9.1) in toluene for 7 days under reflux conditions to give the title compound as yellow foam. MS: m/e=530.7 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08153663B2
Source datasetuspto-grants-2012_04
ORD IDord-cedd423ebd99447aa0668a7c4d700315
Source noteuspto-grants-2012_04