HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexyl isocyanate → 1-(3-Chloro-phenyl)-1-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexyl isocyanate | HCID 18502 | — |
| Reactant | (3-Chloro-phenyl)-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-amine | HCID 66905411 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(3-Chloro-phenyl)-1-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-3-cyclohexyl-urea | HCID 45111025 | — |
Reaction Steps
In analogy to the procedure described in example 1.2, (3-chloro-phenyl)-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-amine was reacted with cyclohexylisocyanate ([3173-53-3]) in toluene for 3 d under reflux conditions to give the title compound as yellow foam. MS: m/e=479.3 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153663B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-3eba4a2feefa4d688e4504bacf568a3d |
| Source note | uspto-grants-2012_04 |