HRID1690654

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66902243

未命名化合物

2 次

结构：C[N+]1(CCCc2ccccc2)CCC(OC(=O)[C@](O)(c2ccccc2)C2CCCC2)CC1.[Br-]

HCID66902412

未命名化合物

HCID66902549

未命名化合物

PRODUCTS

生成物

结构：C[N+]1(CCOc2ccccc2)CCC(OC(=O)[C@](O)(c2ccccc2)C2CCCC2)CC1.[Br-]

HCID66902437

未命名化合物

PROCEDURE

实验过程

This compound is prepared by an analogous method to 4-((R)-2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(3-phenyl-propyl)-piperidinium bromide (Example 9) by replacing 4-Hydroxy-1-methyl-1-(3-phenyl-propyl)-piperidinium bromide (Intermediate K) with 4-hydroxy-1-methyl-1-(2-phenoxy-ethyl)-piperidinium bromide (Intermediate L).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ddc6b3ff96294ef4a801888afe01f787
来源数据集: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08153669B2
来源说明: uspto-grants-2012_04

反应 SMILES

[Br-:1].[CH:2]1([C@@:7]([OH:33])([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:8]([O:10][CH:11]2[CH2:16][CH2:15][N+:14]([CH3:26])([CH2:17][CH2:18]CC3C=CC=CC=3)[CH2:13][CH2:12]2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3]1.[Br-].OC1CC[N+](C)(CCCC2C=CC=CC=2)CC1.[Br-].OC1CC[N+](C)(CC[O:62][C:63]2[CH:68]=[CH:67][CH:66]=[CH:65][CH:64]=2)CC1>>[Br-:1].[CH:2]1([C@@:7]([OH:33])([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)[C:8]([O:10][CH:11]2[CH2:12][CH2:13][N+:14]([CH3:26])([CH2:17][CH2:18][O:62][C:63]3[CH:68]=[CH:67][CH:66]=[CH:65][CH:64]=3)[CH2:15][CH2:16]2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3]1