HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxy-1-methyl-1-(2-phenoxy-ethyl)-piperidinium bromide → 4-((R)-2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(2-phenoxy-ethyl)-piperidinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxy-1-methyl-1-(2-phenoxy-ethyl)-piperidinium bromide | HCID 66902243 | — |
| Reactant | 4-((R)-2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(3-phenyl-propyl)-piperidinium bromide | HCID 66902412 | — |
| Reactant | 4-Hydroxy-1-methyl-1-(3-phenyl-propyl)-piperidinium bromide | HCID 66902549 | — |
| Product | 4-((R)-2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(2-phenoxy-ethyl)-piperidinium bromide | HCID 66902437 | — |
Reaction Steps
This compound is prepared by an analogous method to 4-((R)-2-Cyclopentyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(3-phenyl-propyl)-piperidinium bromide (Example 9) by replacing 4-Hydroxy-1-methyl-1-(3-phenyl-propyl)-piperidinium bromide (Intermediate K) with 4-hydroxy-1-methyl-1-(2-phenoxy-ethyl)-piperidinium bromide (Intermediate L).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08153669B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-ddc6b3ff96294ef4a801888afe01f787 |
| Source note | uspto-grants-2012_04 |