1-oxo-2,3-dihydro-1H-indene-5-carbonitrile → HCID 16046755, compound

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Reaction Steps

A sample of 1-oxo-indan-5-carbonitrile (133.5 mg, 0.85 mmol) (Example 74, step 1) and (4′-Butyl-2-fluoro-biphenyl-3-yl)-hydrazine hydrochloride (250.4, 0.85 mmol) are reacted together as in example 1, step 3 followed by purification by UV triggered reverse phase HPLC to afford the title compound as a white solid. LC/MS calculated for [M+H]+ C26H21FN2: 381.2, found: 381.2.

Provenance & Evidence