Hydracrylonitrile → HCID 24991583, compound

HRID 1690838Notes

Reaction equation

HRID 1690838 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:13][CH:14]([F:16])[F:15])=[C:6]([CH:8]([CH2:11][OH:12])[C:9]#[N:10])[CH:7]=1.[OH:17][CH2:18][CH2:19]C#N>>[C:18]([O:12][CH2:11][CH:8]([C:6]1[CH:7]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=1[O:13][CH:14]([F:15])[F:16])[C:9]#[N:10])(=[O:17])[CH3:19]

Participants

3

Reactant 2

HCID 8011HydracrylonitrileHCID 66906224HCID 66906224, compound

Product 1

HCID 24991583HCID 24991583, compound

Procedure

This ester was prepared using the procedure described in Example 5, except 2-(5-chloro-2-(difluoromethoxy)phenyl)-3-hydroxypropanenitrile was used in place of 2-(2-chloro-5-(difluoromethoxy)phenyl)-3-hydroxypropanenitrile. The preparation of 2-5-chloro-2-(difluoromethoxy)phenyl)-3-hydroxypropanenitrile is described in Example 4. The recovered ester product was a colorless oil.

Sources & evidence

ORD record
ord-789dd88756d24ef08b27fdcf1092d118
Source dataset
uspto-grants-2012_04
Patent number
US08153688B2

Reaction notes

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