Hydracrylonitrile → HCID 56952235, compound

HRID 1690849Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:11]([OH:13])[CH3:12])[C:9]#[N:10])=[CH:4][CH:3]=1.[OH:14][CH2:15][CH2:16]C#N>>[C:15]([O:13][CH:11]([CH3:12])[CH:8]([C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=1)[C:9]#[N:10])(=[O:14])[CH3:16]

Participants

Reactant 2

HCID 8011Hydracrylonitrile

HCID 66906157HCID 66906157, compound2×

Product 1

HCID 56952235HCID 56952235, compound

Procedure

This ester was prepared using the procedure described in Example 5, except 2-(4-methylphenyl)-3-hydroxybutanenitrile in place of 2-2-chloro-5-(difluoromethoxy)phenyl)-3-hydroxypropanenitrile in the above described procedure. The preparation of 2-(4-methylphenyl)-3-hydroxybutanenitrile is described in Example 17. The recovered ester product was a colorless oil (85% yield).

Sources & evidence

ORD record: ord-6ea7c5b75fc843d094e39fdce77e7636
Source dataset: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08153688B2

Reaction notes

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