HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1691595Generated: November 1, 2026
Triethylamine → tert-Butyl 4-(3,5-dinitropyridin-2-yl)aminobutanoate
https://huagongshe.com/reaction/1691595
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Chloro-3,5-dinitropyridine | HCID 75738 | — |
| Reactant | Tert-butyl 4-aminobutanoate hydrochloride | HCID 24750478 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | tert-Butyl 4-(3,5-dinitropyridin-2-yl)aminobutanoate | HCID 86643266 | — |
Reaction Steps
A suspension of 3 g (14.74 mmol) of 2-chloro-3,5-dinitropyridine in dioxane is admixed with 3.46 g (17.69 mmol) of tert-butyl 4-aminobutanoate hydrochloride and then with 4.21 ml (22.11 mmol) of triethylamine. The reaction mixture is stirred at 60° C. for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08153796B2 |
|---|
| Source dataset | uspto-grants-2012_04 |
|---|
| ORD ID | ord-81571dfccc5241cbab40c0fa1bc9c7dc |
|---|
| Source note | uspto-grants-2012_04 |
|---|
