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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1691847Generated: November 1, 2026

(S)-2-(4-fluoro-phenyl)-2,3-dihydro-1H-pyridin-4-one → (S)-2-(4-fluoro-phenyl)-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid (2-isopropyl-4,5-dimethoxy-phenyl)-amide

https://huagongshe.com/reaction/1691847

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(4-fluoro-phenyl)-2,3-dihydro-1H-pyridin-4-oneHCID 59377679—
Reactant1-Isocyanato-2-isopropyl-4,5-dimethoxy-benzeneHCID 59377775—
Product(S)-2-(4-fluoro-phenyl)-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid (2-isopropyl-4,5-dimethoxy-phenyl)-amideHCID 59377855—

Reaction Steps

1-Isocyanato-2-isopropyl-4,5-dimethoxy-benzene was reacted with (S)-2-(4-fluoro-phenyl)-2,3-dihydro-1H-pyridin-4-one following the procedure of step 3 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08153809B2
Source datasetuspto-grants-2012_04
ORD IDord-027e0c7191bf4978823e97e30caf6b99
Source noteuspto-grants-2012_04