huagongshe.com
HRID1692656

反应详情

EQUATION

反应方程式

HRID 1692656 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1cccc2[nH]ccc12
HCID2763173

Indole-4-boronic acid

C8H8BNO2

结构：CC(=O)OCCn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(Cl)nc21
HCID58015224

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(O)c1nc2c(N3CCOCC3)nc(-c3cccc4[nH]ccc34)nc2n1CCO
HCID44477428

未命名化合物

PROCEDURE

实验过程

2-(2-Chloro-8-(2-hydroxypropan-2-yl)-6-morpholino-9H-purin-9-yl)ethyl acetate (165 mg) was treated with indole-4-boronic acid via General Procedure A and purified via reverse phase HPLC to give 21 mg of 101 as a white solid. MS (Q1) 423.2 (M)+

WORKUP

后处理

  1. custompurified via reverse phase HPLC