huagongshe.com
HRID1692658

反应详情

EQUATION

反应方程式

HRID 1692658 的结构方程式

REACTANTS

反应物

2
结构：CCCCBr
HCID8002

1-Bromobutane

C4H9Br

结构：CC(C)(O)c1nc2c(N3CCOCC3)nc(Cl)nc2[nH]1
HCID178458928

未命名化合物

PRODUCTS

生成物

1
结构：CCCCn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(Cl)nc21
HCID58015212

9-Butyl-2-chloro-α,α-dimethyl-6-(4-morpholinyl)-9H-purine-8-methanol

C16H24ClN5O2

PROCEDURE

实验过程

2-(2-Chloro-6-morpholino-9H-purin-8-yl)propan-2-ol 100 mg was treated with bromobutane via General Procedure C to give crude intermediate 2-(9-butyl-2-chloro-6-morpholino-9H-purin-8-yl)propan-2-ol which was treated with 2-aminopyrimidine-5-boronic acid, pinacol ester via General Procedure A and was purified via reverse phase HPLC to give 55 mg of 103 as a white solid. MS (Q1) 413.3 (M)+.