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HRID1692659

反应详情

EQUATION

反应方程式

HRID 1692659 的结构方程式

REACTANTS

反应物

2
结构：CCCI
HCID33643

1-Iodopropane

C3H7I

结构：CC(C)(O)c1nc2c(N3CCOCC3)nc(Cl)nc2[nH]1
HCID178458928

未命名化合物

PRODUCTS

生成物

1
结构：CCCn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(Cl)nc21
HCID58015223

未命名化合物

PROCEDURE

实验过程

2-(2-Chloro-6-morpholino-9H-purin-8-yl)propan-2-ol (100 mg) was treated with iodopropane via General Procedure C to give crude intermediate 2-(2-chloro-6-morpholino-9-propyl-9H-purin-8-yl)propan-2-ol which was treated with 2-aminopyrimidine-5-boronic acid, pinacol ester via General Procedure A and was purified via reverse phase HPLC to give 34 mg of 104 as a white solid. MS (Q1) 399.3 (M)+.