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HRID1692676

反应详情

EQUATION

反应方程式

HRID 1692676 的结构方程式

REACTANTS

反应物

2
结构：Nc1ncc(B(O)O)cn1
HCID17750211

(2-Aminopyrimidin-5-yl)boronic acid

C4H6BN3O2

结构：Cn1cnc2c(N3CCOCC3)nc(Cl)nc21
HCID71500687

2-Chloro-9-methyl-6-(4-morpholinyl)-9H-purine

C10H12ClN5O

PRODUCTS

生成物

1
结构：Cn1cnc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21
HCID44543764

未命名化合物

PROCEDURE

实验过程

4-(2-Chloro-9-methyl-9H-purin-6-yl)morpholine (95 mg) was reacted with 2-aminopyrimidine-5-boronic acid, pinacol ester via General Procedure A and purified via reverse phase HPLC to give 26.1 mg of 127 as a white solid. MS (Q1) 313.2 (M)+

WORKUP

后处理

  1. custompurified via reverse phase HPLC