HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazin-2-one → 4-(2-(2-(3-hydroxyphenyl)-6-morpholino-9H-purin-9-yl)acetyl)piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazin-2-one | HCID 231360 | — |
| Reactant | 2-(2-(3-hydroxyphenyl)-6-morpholino-9H-purin-9-yl)acetic acid | HCID 66909814 | — |
| Product | 4-(2-(2-(3-hydroxyphenyl)-6-morpholino-9H-purin-9-yl)acetyl)piperazin-2-one | HCID 44543987 | — |
Reaction Steps
Crude 2-(2-(3-hydroxyphenyl)-6-morpholino-9H-purin-9-yl)acetic acid (50 mg) was reacted with piperazin-2-one via General Procedure F and purified via reverse phase HPLC to give 1.9 mg of 139 as a white solid. MS (Q1) 438.2 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158624B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-74fdecfba6004179be928f06f3ad501d |
| Source note | uspto-grants-2012_04 |