HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → HCID 54498727, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | Methyl 2-(bromomethyl)benzoate | HCID 2734813 | — |
| Product | HCID 54498727 | HCID 54498727 | 92.5% |
Reaction Steps
step 1—A solution of methyl 2-bromomethyl-benzoate (9.99 g, 43.6 mmol) and triethylphosphite (7.25 g, 43.6 mmol) was heated to 150° C. for 5 h. The reaction mixture as cooled to RT then purified by SiO2 chromatography to afford 11.55 g of 2-(diethoxy-phosphorylmethyl)-benzoic acid methyl ester (72)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158631B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-8cce58e234614ffc9411479b7e16b0eb |
| Source note | uspto-grants-2012_04 |