反应详情

温度

45 °C

To a solution of 2-(4-pyridin-4-yl-phenylsulfamoyl)-indole-1-carboxylic acid tert-butyl ester (0.030 g) in ethyl acetate (1.0 ml) was added 3.5 N HCl/ethyl acetate (2.0 ml). The reaction mixture was stirred at 45° C. for 8 h, then diluted with ether (40 ml). The precipitate was collected, washed with ether and dried under high vacuum over P2O5 to obtain the title compound (0.025 g) as a colorless amorphous powder. MS (ISP): 350.4 (M+H)+

1. customThe precipitate was collected
2. washwashed with ether
3. dry with materialdried under high vacuum over P2O5