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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1693131Generated: November 2, 2026

4-Bromo-2-(trifluoromethyl)aniline → HCID 59759981, compound

https://huagongshe.com/reaction/1693131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-(trifluoromethyl)anilineHCID 67960—
ReactantHCID 59759976HCID 59759976—
SolventPyridineHCID 1049—
ProductHCID 59759981HCID 5975998120.7%

Reaction Steps

This compound was prepared in analogy to Example 1 starting from 2-chlorosulfonyl-5-fluoro-3-methyl-indole-1-carboxylic acid tert-butyl ester (0.29 g) and 2-amino-5-bromobenzotrifluoride (2.0 g) in pyridine (5 ml) by stirring for 7 days at rt to obtain the title compound (0.095 g) as a colorless foam. MS (ISN): 551.4, 549.3 (M−H)−

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08158655B2
Source datasetuspto-grants-2012_04
ORD IDord-476bdf56e4ae4f3598ae91a977ebbf96
Source noteuspto-grants-2012_04