Tetrabutylammonium Fluoride → HCID 57827681, compound

HRID 1693190Notes

Reaction equation

HRID 1693190 reaction equation
[F-].C([N+](CCCC)(CCCC)CCCC)CCC.C([Si]([O:36][CH2:37][CH2:38][CH:39]([O:43][CH2:44][CH3:45])[CH2:40][CH:41]=[CH2:42])(C1C=CC=CC=1)C1C=CC=CC=1)(C)(C)C>C1COCC1>[CH2:44]([O:43][CH:39]([CH2:40][CH:41]=[CH2:42])[CH2:38][CH2:37][OH:36])[CH3:45]

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 57827623HCID 57827623, compound

Product 1

HCID 57827681HCID 57827681, compoundYield 71.2%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Tetrabutylammonium fluoride (1 M solution in THF, 13 mL) was added to a solution of tert-butyl-(3-ethoxy-5-hexenyloxy)diphenylsilane (4.1 g) in THF (40 mL) at room temperature, followed by stirring for one hour. The reaction solution was concentrated. The resulting crude product was purified by silica gel column chromatography to obtain the title compound (1.1 g).

Workup

  1. concentrationThe reaction solution was concentrated
  2. customThe resulting crude product was purified by silica gel column chromatography

Sources & evidence

ORD record
ord-565a41e1d0404d4c9adebd5585fb3325
Source dataset
uspto-grants-2012_04
Patent number
US08158620B2

Reaction notes

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