Phenethylamine → HCID 11266547, compound

HRID 1693427Notes

Reaction equation

HRID 1693427 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[CH:10]=[C:9]([C:11]([OH:13])=O)[NH:8][C:5]2=[CH:6][N:7]=1.[CH2:14]([NH2:22])[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:14]([NH:22][C:11]([C:9]1[NH:8][C:5]2=[CH:6][N:7]=[C:2]([Cl:1])[CH:3]=[C:4]2[CH:10]=1)=[O:13])[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 1001PhenethylamineHCID 446307045-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid

Product 1

HCID 11266547HCID 11266547, compound

Procedure

The title compound was prepared as outlined in EXAMPLE 1 from 5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (Preparation 18) and phenethylamine. The product was purified by mass directed purification to give the title compound as an orange solid. δH (CD3OD): 2.94 (2H, t), 3.63 (2H, t), 7.00 (1H, s), 7.15-7.30 (5H, m), 7.64 (1H, s), 8.57 (1H, s); m/z (ES+)=300 [M+H]+.

Workup

  1. customThe title compound was prepared
  2. customThe product was purified by mass
  3. custompurification

Sources & evidence

ORD record
ord-fb448052289846f28f900ca6d6fb56c9
Source dataset
uspto-grants-2012_04
Patent number
US08158622B2

Reaction notes

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