1,2-Ethanediamine, N1-phenyl- → 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid (2-phenylaminoethyl)amide

HRID 1693432Notes

Reaction equation

HRID 1693432 reaction equation
[NH:1]1[C:5]2=[CH:6][N:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[C:2]1[C:10]([OH:12])=O.[C:13]1([NH:19][CH2:20][CH2:21][NH2:22])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([NH:19][CH2:20][CH2:21][NH:22][C:10]([C:2]2[NH:1][C:5]3=[CH:6][N:7]=[CH:8][CH:9]=[C:4]3[CH:3]=2)=[O:12])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 742701,2-Ethanediamine, N1-phenyl-HCID 218190021H-Pyrrolo(2,3-c)pyridine-2-carboxylic acid

Product 1

HCID 117375791H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid (2-phenylaminoethyl)amide

Procedure

The title compound was prepared as outlined in EXAMPLE 1 from 1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (Preparation 15) and 2-phenylaminoethylamine to give the title compound as a pale yellow solid. δH (CD3OD): 3.37 (2H, t), 3.63 (2H, t), 6.61 (1H, t), 6.69 (2H, d), 7.08-7.13 (2H, m), 7.64 (1H, d), 8.10 (1H, d), 8.78 (1H, s); m/z (ES+)=281 [M+H]+.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-ed9b6c1ab41b4e9ba162fc1e69e79d26
Source dataset
uspto-grants-2012_04
Patent number
US08158622B2

Reaction notes

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