2-(4-Benzylpiperazin-1-yl)ethan-1-amine → 5-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid [2-(4-benzylpiperazin-1-yl)ethyl]amide

HRID 1693436Notes

Reaction equation

HRID 1693436 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[CH:10]=[C:9]([C:11]([OH:13])=O)[NH:8][C:5]2=[CH:6][N:7]=1.[CH2:14]([N:21]1[CH2:26][CH2:25][N:24]([CH2:27][CH2:28][NH2:29])[CH2:23][CH2:22]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([N:21]1[CH2:22][CH2:23][N:24]([CH2:27][CH2:28][NH:29][C:11]([C:9]2[NH:8][C:5]3=[CH:6][N:7]=[C:2]([Cl:1])[CH:3]=[C:4]3[CH:10]=2)=[O:13])[CH2:25][CH2:26]1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 27353312-(4-Benzylpiperazin-1-yl)ethan-1-amineHCID 446307045-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid

Product 1

HCID 117498795-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid [2-(4-benzylpiperazin-1-yl)ethyl]amide

Procedure

The title compound was prepared as outlined in EXAMPLE 1 from 5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (Preparation 18) and 4-benzylpiperazin-1 ylethylamine. The product was purified by mass directed purification to give the title compound as an orange solid. m/z (ES+)=398 [M+H]+; RT=2.75 min.

Workup

  1. customThe title compound was prepared
  2. customThe product was purified by mass
  3. custompurification

Sources & evidence

ORD record
ord-393ff36ea8bb4c8b81d77170f3299917
Source dataset
uspto-grants-2012_04
Patent number
US08158622B2

Reaction notes

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