Benzyl Isothiocyanate → HCID 11631270, compound

HRID 1693580Notes

Reaction equation

HRID 1693580 reaction equation
[CH2:1]([N:8]=[C:9]=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:11]1[O:19][C:18]2[CH:17]=[CH:16][C:15]([N:20]=[C:21]=[O:22])=[CH:14][C:13]=2[O:12]1.C([O:25]CC)C>>[CH2:1]([N:8]1[C:9](=[O:25])[S:10][N:20]([C:15]2[CH:16]=[CH:17][C:18]3[O:19][CH2:11][O:12][C:13]=3[CH:14]=2)[C:21]1=[O:22])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 2346Benzyl IsothiocyanateHCID 3283Diethyl EtherHCID 52232135-Isocyanato-1,3-dioxaindane

Product 1

HCID 11631270HCID 11631270, compound

Procedure

Reagents: Benzylisothiocyanate (6.5 mmol, 0.85 mL), 3,4-(methylenedioxy)phenyl-isocyanate (6.5 mmol, 1.06 mL) and SO2Cl2 (6.5 mmol, 0.52 mL) in diethyl ether (25 mL). Isolation: filtration of reaction mixture. Purification: recrystallization from MeOH.

Workup

  1. filtrationIsolation: filtration of reaction mixture
  2. customPurification
  3. customrecrystallization from MeOH

Sources & evidence

ORD record
ord-90deac2e8fe74c3d93a2aca1e4661afa
Source dataset
uspto-grants-2012_04
Patent number
US08158661B2

Reaction notes

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