HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59186885, compound → HCID 25064544, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59186885 | HCID 59186885 | — |
| Reactant | HCID 178448297 | HCID 178448297 | — |
| Product | HCID 25064544 | HCID 25064544 | 16% |
Reaction Steps
The title compound was prepared using General method A starting from (2R)-2-[(2-amino-5-mercapto[1,3]thiazolo[4,5-d]pyrimidin-7-yl)(methyl)amino]pentan-1-ol (96 mg, 0.32 mmol) and 2-chloro-5-[(1R)-1-chloroethyl]pyridine (85 mg, 0.48 mmol). Purification by flash column chromatography (eluent DCM:ethyl acetate) yielded 22 mg (16% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158785B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-443ace8a44dc490b855dd17e32755020 |
| Source note | uspto-grants-2012_04 |