Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1694554Generated: October 27, 2026

HCID 59186885, compound → HCID 25064752, compound

https://huagongshe.com/reaction/1694554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59186885HCID 59186885—
ReactantHCID 178448295HCID 178448295—
ProductHCID 25064752HCID 2506475222.1%

Reaction Steps

The title compound was prepared using General Method A starting from (2R)-2-[(2-amino-5-mercapto[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]pentan-1-ol (70 mg, 0.245 mmol) and 2-chloro-5-[(1R)-1-chloroethyl]pyridine (Example 6b, 52 mg, 0.29 mmol). Purification by preparative HPLC yielded 23 mg (22% yield) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08158785B2
Source datasetuspto-grants-2012_04
ORD IDord-64fa83e8d6c349739c4cf54ab983774d
Source noteuspto-grants-2012_04