Ethanesulfonyl chloride → HCID 67280503, compound
Reaction equation
[CH2:1]([NH:8][C:9]1[N:14]=[CH:13][C:12]([Br:15])=[CH:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:16]([S:18](Cl)(=[O:20])=[O:19])[CH3:17]>>[Br:15][C:12]1[CH:13]=[N:14][C:9]([N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[S:18]([CH2:16][CH3:17])(=[O:20])=[O:19])=[N:10][CH:11]=1Participants
3
Procedure
The subtitle compound was prepared by the method of example 38 step (i) using benzyl-(5-bromo-pyrimidin-2-yl)-amine and ethanesulphonyl chloride, yield 0.31 g.
Sources & evidence
- ORD record
- ord-ffbd46973550455d900077df951178c7
- Source dataset
- uspto-grants-2012_04
- Patent number
- US08158820B2
Reaction notes
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