反应详情

5% Pt/C (0.088 g) was added to a solution of the product from step (i) in ethanol (20 ml) and hydrogenated at RT and 1 bar for 18 h. Extra Pt/C (0.1 g) was added and hydrogenated for a further 3 h at 2 bar. The catalyst was removed by filtration and the filtrate evaporated to leave a solid residue. The residue was purified by chromatography on silica eluting with 50% EtOAc/isohexane. Yield 0.083 g.

1. waithydrogenated for a further 3 h at 2 bar
2. customThe catalyst was removed by filtration
3. customthe filtrate evaporated
4. customto leave a solid residue
5. customThe residue was purified by chromatography on silica eluting with 50% EtOAc/isohexane