Dimethylformamide → 3-Chloro-4-iodo-N,N-dimethylbenzenesulfonamide

Beteiligte Stoffe

Reaktionsschritte

Sodium hydride (0.33 g) was added to a solution of the product from step (i) (1.2 g) in DMF (25 ml) and stirred for 20 min. Methyl iodide (0.5 ml) was added dropwise and then stirred for a further 1 h. The reaction mixture was quenched with water, extracted with EtOAc, dried (MgSO4) and evaporated. The residue was treated with ether to give to give the subtitle compound as a white solid. Yield 0.45 g.

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