HCID 178478049, compound → HCID 178420080, compound

Participants

Reaction Steps

To a stirred solution of 50 mg (0.19 mmol) 4-(3-chloro-biphenyl-2-ylmethyl)-1H-imidazole in 40 ml methanol was added 40 mg of 10% palladium on charcoal and the mixture was then stirred for 16 h at room temperature under hydrogen at 0.6 bar excess pressure. The mixture was then filtered and the filtrate concentrated in vacuo to afford 25 mg (57%) of the title compound as a white crystalline solid. MS (ISP): 235.1 ([M+H]+).

Provenance & Evidence