Lithium Hydroxide → Benzenesulfonic acid, 4-amino-, monolithium salt

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Reaction Steps

Next, a sulfanilate lithium salt precursor is prepared according to step 2 in FIG. 8. Sulfanilic acid (1.35 g, 7.8 mmol) and LiOH (0.187 g, 7.8 mmol) were added in water (10 mL) with constant stirring. This step results in an available lone pair of electrons on the amino group to react with the acid chloride at the next and final step. After stirring 20 min, the clear solution was then dried in vacuum overnight to obtain a dried sulfanilate lithium salt precursor. The solid was used as the starting material in the final step.

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