反应详情

A solution of the product from step d) (73 mg) in TFA (3 ml) was stirred for 2 h. The solvent was removed in vacuo, water was added and the mixture was extracted with dichloromethane (three times). The organic extracts were dried (MgSO4), evaporated and triturated with ether to give the title compound (46 mg) as a white solid. M.p. 140-2° C.

1. customThe solvent was removed in vacuo, water
2. additionwas added
3. extractionthe mixture was extracted with dichloromethane (three times)
4. dry with materialThe organic extracts were dried (MgSO4)
5. customevaporated
6. customtriturated with ether