HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1-Ethyl-1H-indol-3-yl)-3-oxo-propionitrile → HCID 178462497, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1-Ethyl-1H-indol-3-yl)-3-oxo-propionitrile | HCID 67188025 | — |
| Reactant | HCID 178418806 | HCID 178418806 | — |
| Product | HCID 178462497 | HCID 178462497 | 70% |
Reaction Steps
The product was prepared according to general procedure for aminopyrazole synthesis (route A2) starting from 3-(1-ethyl-1H-indol-3-yl)-3-oxo-propionitrile (820 mg, 3.87 mmol, 1.0 eq). The solvent was removed under reduced pressure; the solid residue was washed with EtOH to obtain the title product (612 mg, 70% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163729B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-8ad9340eb697481390c7c7aeaf98867b |
| Source note | uspto-grants-2012_04 |