2-Aminopropanol → HCID 66643963, compound

Participants

Reaction Steps

As described for example 55, 5-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (200 mg, 0.6 mmol) was converted, using DL-2-amino-1-propanol instead of 2-amino-2-methyl-1-propanol, to the title compound (155 mg, 66%) which was obtained as a white solid. MS: m/e=389.1 [M+H]+.

Provenance & Evidence