HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 49793043, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 66643882 | HCID 66643882 | — |
| Product | HCID 49793043 | HCID 49793043 | 60% |
Reaction Steps
As described for example 122, 5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2-methyl-2H-pyrazole-3-carboxylic acid was converted, using ammonia instead of isopropylamine, to the title compound (19 mg, 60%) which was obtained as a white solid. MS: m/e=327.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-e0118b18d4e1490694a02d6fe29e580b |
| Source note | uspto-grants-2012_04 |