2-Amino-2-methyl-1-propanol → HCID 178434999, compound

Participants

Reaction Steps

As described for example 132, 5-{(E)-2-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-yl]-vinyl}-2H-pyrazole-3-carboxylic acid was converted, using 2-hydroxy-1,1-dimethylethylamine instead of morpholine, to the title compound (11 mg, 36%) which was obtained as an off white solid. MS: m/e=385.2 [M+H]+.

Provenance & Evidence