HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 59568427, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 66643816 | HCID 66643816 | — |
| Product | HCID 59568427 | HCID 59568427 | 20% |
Reaction Steps
As described for example 144, 5-{[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-amino}-2-methyl-2H-pyrazole-3-carboxylic acid was converted, using ammonia instead of 2-hydroxy-2-methylpropylamine, to the title compound (12 mg, 20%) which was obtained as an off white solid. MS: m/e=330.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f9b5d03d318b420797a5b3914416a98d |
| Source note | uspto-grants-2012_04 |