HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 49793112, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-{[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-amino}-2H-pyrazole-3-carboxylic acid | HCID 66643764 | — |
| Product | HCID 49793112 | HCID 49793112 | 29% |
Reaction Steps
As described for example 152, 5-{[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethyl]-amino}-2H-pyrazole-3-carboxylic acid was converted, using ammonia instead of 2-hydroxy-2-methylpropylamine, to the title compound (17 mg, 29%) which was obtained as an off white solid. MS: m/e=316.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163728B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-bf4f818dd2844c898de557c29e5d79df |
| Source note | uspto-grants-2012_04 |