HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 57960319, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromoacetamide | HCID 69632 | — |
| Reactant | HCID 67269726 | HCID 67269726 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 57960319 | HCID 57960319 | — |
| Product | HCID 57960679 | HCID 57960679 | — |
Reaction Steps
4-(3-Aminopyridine-2-yl)piperidin-4-ol hydrochloride was allowed to undergo the reaction with 20% sulfuric acid. This was allowed to undergo the reaction with potassium carbonate and 2-bromoacetamide in acetonitrile to obtain 2-(3-amino-3′,6′-dihydro-2,4′-bipyridine-1′(2′H)-yl)acetamide and 2-[4-(3-aminopyridine-2-yl)-4-hydroxypiperidin-1-yl]acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163746B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-711a623ee54044b796c44f6e338db2e7 |
| Source note | uspto-grants-2012_04 |