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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1695587Generated: October 31, 2026

7-Methoxy-2,3-dihydro-1H-inden-1-amine → HCID 178488350, compound

https://huagongshe.com/reaction/1695587

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Methoxy-2,3-dihydro-1H-inden-1-amineHCID 18619881—
Reactanttert-Butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silaneHCID 46855450—
ProductHCID 178488350HCID 17848835073.4%

Reaction Steps

Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (3.89 g, 12.0 mmol; HPLC: 4.446 min) and the above described rac-7-methoxy-indan-1-ylamine (1.96 g, 12.0 mmol; HPLC 0.4 min) according to the procedure described for Example 1. Obtained the title compound as a yellow solid (2.99 g, 73%; HPLC 1.683 min), MS (ISP) m/e=340.1 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163740B2
Source datasetuspto-grants-2012_04
ORD IDord-6e92ab60f08b4b1ca98fe91f34f12a20
Source noteuspto-grants-2012_04