1-Isopropylpiperazine → HCID 178489489, compound

Participants

Reaction Steps

Prepared from 2-chloro-N-[2-(2-methoxy-benzylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (Example 26 step A) (50 mg, 0.129 mmol, HPLC 0.889 min 81%) and N-isopropylpiperazine (1 ml, 8 mmol) according to the procedure described for Example 3 step B. Obtained the title compound as a white foam (150 mg, 72%, HPLC 0.492 min 87%), MS (ISP) m/e=452.3 [(M+H)+].

Provenance & Evidence