1-Methylpiperazine → HCID 178480915, compound

Participants

Reaction Steps

Prepared from rac-2-chloro-N-[2-(6-fluoro-2,3-dihydro-benzofuran-3-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (Example 42 step A) (50 mg, 0.133 mmol, HPLC 1.056 min) and 1-methylpiperazine (300 ul, 2.66 mmol) according to the procedure described for Example 3 step B. Obtained the title compound as a white solid (58 mg, 99%, HPLC 0.468 min 100%), MS (ISP) m/e=440.3 [(M+H)+].

Provenance & Evidence