HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-2,3-dihydro-1H-inden-1-amine → HCID 178505421, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-2,3-dihydro-1H-inden-1-amine | HCID 16666328 | — |
| Reactant | (5-Bromo-2-isothiocyanato-benzyloxy)-tert-butyl-dimethyl-silane | HCID 87311762 | — |
| Product | HCID 178505421 | HCID 178505421 | 69% |
Reaction Steps
Prepared from (5-bromo-2-isothiocyanato-benzyloxy)-tert-butyl-dimethyl-silane (Example 32, step B) (4.0 g, 11.2 mmol) and rac-5-fluoro-indan-1-ylamine (CAS 148960-33-2) (1.69 mg, 11.2 mmol) according to the procedure described for Example 1. Obtained the title compound as a light brown oil (2.77 g, 69%), MS (ISP) m/e=361.1 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-c2b7ed34aae443f6894374b92fa57718 |
| Source note | uspto-grants-2012_04 |