2-Amino-4-(trifluoromethyl)pyrimidine → HCID 178488333, compound

Participants

Reaction Steps

The title compound (135 mg, 59%), yellow foam, MS (ISP): m/e=458.2 (M+H+), was prepared in accordance with the general method of Example 35 from rac-(6-bromo-4H-benzo[d][1,3]oxazin-2-yl)-(4-methoxy-2,3-dihydro-benzofuran-3-yl)-amine (example 54) (188 mg, 0.5 mmol) and commercially available 2-amino-4-trifluoromethyl-pyrimidine (163 mg, 1.0 mmol).

Provenance & Evidence