HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanol, 1-amino-2-methyl- → HCID 178459316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanol, 1-amino-2-methyl- | HCID 95102 | — |
| Reactant | HCID 178520800 | HCID 178520800 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178459316 | HCID 178459316 | 52.3% |
Reaction Steps
Prepared from 2-chloro-N-[2-((R)-indan-1-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (Example 3 step A) (100 mg, 0.281 mmol) and 1-amino-2-methyl-propan-2-ol (126 mg, 1.405 mmol) in acetonitrile (1 ml) according to the procedure described for Example 3 step B. Obtained the title compound as a white solid (60 mg, 52%), MS (ISP) m/e=409.3 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-2d1b56b92d864e2eb329ad504c2a1d55 |
| Source note | uspto-grants-2012_04 |