HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-(trifluoromethyl)pyrimidine → HCID 178488332, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-(trifluoromethyl)pyrimidine | HCID 595915 | — |
| Reactant | 6-bromo-N-(7-methoxy-2,3-dihydro-1H-inden-1-yl)-4H-3,1-benzoxazin-2-amine | HCID 178488326 | — |
| Product | HCID 178488332 | HCID 178488332 | 62% |
Reaction Steps
The title compound (141 mg, 62%), yellow foam, MS (ISP): m/e=456.3 (M+H+), was prepared in accordance with the general method of Example 35 from rac-(6-bromo-4H-benzo[d][1,3]oxazin-2-yl)-(7-methoxy-indan-1-yl)-amine (Example 74) (187 mg, 0.5 mmol) and commercially available 2-amino-4-trifluoromethyl-pyrimidine (163 mg, 1.0 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-cf3394d5137e4716a4b159b11ff46b94 |
| Source note | uspto-grants-2012_04 |