Cycloheptylamine → HCID 178526442, compound

HRID 1695648Notes

Reaction equation

C([Si]([O:8][CH2:9][C:10]1[CH:15]=[C:14]([N+:16]([O-:18])=[O:17])[CH:13]=[CH:12][C:11]=1[N:19]=[C:20]=S)(C)C)(C)(C)C.[CH:22]1([NH2:29])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH:22]1([NH:29][C:20]2[O:8][CH2:9][C:10]3[CH:15]=[C:14]([N+:16]([O-:18])=[O:17])[CH:13]=[CH:12][C:11]=3[N:19]=2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

Reactant 2

HCID 2899Cycloheptylamine

HCID 46855450tert-Butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane

Product 1

HCID 178526442HCID 178526442, compoundYield 100%

Procedure

Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (5.0 g, 15 mmol) and cycloheptylamine (1.8 g, 16 mmol) according to the procedure described for Example 1. Obtained the title compound as a yellow foam (4.3 g, 100%), MS (ISP) m/e=288.3 [(M−H)+].

Sources & evidence

ORD record: ord-d996c924fbaf432c8e0ef7f060404359
Source dataset: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08163740B2

Reaction notes

Loading…